| Signaling during platelet adhesion and activation Z Li, MK Delaney, KA O'Brien, X Du Arteriosclerosis, thrombosis, and vascular biology 30 (12), 2341-2349, 2010 | 1026 | 2010 |
| Inside-out integrin signalling MH Ginsberg, X Du, EF Plow Current opinion in cell biology 4 (5), 766-771, 1992 | 645 | 1992 |
| Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa) X Du, EF Plow, AL Frelinger III, TE O'Toole, JC Loftus, MH Ginsberg Cell 65 (3), 409-416, 1991 | 613 | 1991 |
| Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function. AL Frelinger 3rd, XP Du, EF Plow, MH Ginsberg Journal of Biological Chemistry 266 (26), 17106-17111, 1991 | 435 | 1991 |
| Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway G Zhang, J Han, EJ Welch, RD Ye, TA Voyno-Yasenetskaya, AB Malik, ... The Journal of Immunology 182 (12), 7997-8004, 2009 | 414 | 2009 |
| Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. TE O'Toole, JC Loftus, XP Du, AA Glass, ZM Ruggeri, SJ Shattil, EF Plow, ... Cell regulation 1 (12), 883-893, 1990 | 349 | 1990 |
| New concepts and mechanisms of platelet activation signaling B Estevez, X Du Physiology 32 (2), 162-177, 2017 | 344 | 2017 |
| A stimulatory role for cGMP-dependent protein kinase in platelet activation Z Li, X Xi, M Gu, R Feil, DY Richard, M Eigenthaler, F Hofmann, X Du Cell 112 (1), 77-86, 2003 | 323 | 2003 |
| Inside-out, outside-in, and inside–outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction B Shen, MK Delaney, X Du Current opinion in cell biology 24 (5), 600-606, 2012 | 291 | 2012 |
| G protein subunit Gα13 binds to integrin αIIbβ3 and mediates integrin “outside-in” signaling H Gong, B Shen, P Flevaris, C Chow, SCT Lam, TA Voyno-Yasenetskaya, ... Science 327 (5963), 340-343, 2010 | 287 | 2010 |
| Long range propagation of conformational changes in integrin alpha IIb beta 3. X Du, M Gu, JW Weisel, C Nagaswami, JS Bennett, R Bowditch, ... Journal of Biological Chemistry 268 (31), 23087-23092, 1993 | 279 | 1993 |
| Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane X Du, L Beutler, C Ruan, PA Castaldi, MC Berndt | 260 | 1987 |
| Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK–dependent integrin outside-in retractile signaling pathway P Flevaris, Z Li, G Zhang, Y Zheng, J Liu, X Du Blood, The Journal of the American Society of Hematology 113 (4), 893-901, 2009 | 228 | 2009 |
| Calpain Cleavage of the Cytoplasmic Domain of the Integrin β2 Subunit (∗) X Du, TC Saido, S Tsubuki, FE Indig, MJ Williams, MH Ginsberg Journal of Biological Chemistry 270 (44), 26146-26151, 1995 | 219 | 1995 |
| A molecular switch that controls cell spreading and retraction P Flevaris, A Stojanovic, H Gong, A Chishti, E Welch, X Du The Journal of cell biology 179 (3), 553-565, 2007 | 202 | 2007 |
| Ristocetin-dependent reconstitution of binding of von Willebrand factor to purified human platelet membrane glycoprotein Ib-IX complex MC Berndt, X Du, WJ Booth Biochemistry 27 (2), 633-640, 1988 | 195 | 1988 |
| Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin αIIbβ3 Z Li, G Zhang, R Feil, J Han, X Du Blood 107 (3), 965-972, 2006 | 192 | 2006 |
| Signaling and regulation of the platelet glycoprotein Ib–IX–V complex X Du Current opinion in hematology 14 (3), 262-269, 2007 | 191 | 2007 |
| Identification of a Binding Sequence for the 14-3-3 Protein within the Cytoplasmic Domain of the Adhesion Receptor, Platelet Glycoprotein Ibα (∗) X Du, JE Fox, S Pei Journal of Biological Chemistry 271 (13), 7362-7367, 1996 | 189 | 1996 |
| A murine antiglycoprotein Ib complex monoclonal antibody, SZ 2, inhibits platelet aggregation induced by both ristocetin and collagen CG Ruan, XP Du, XD Xi, PA Castaldi, MC Berndt | 179 | 1987 |
Mark H GinsbergUniversity of California San DiegoVerified email at ucsd.edu
